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Home Up Rationale Overview Rule Out Step 1 Rule Out Step 2 Rule Out Step 3 Rule Out Step 4 References
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Childhood
Disabilities: Early
Identification and Intervention
Rule Out Model for the Early Identification and Treatment of Children with
Developmental Disabilities
Rule Out Step 1
Content:
Rule
Out Step 1: Background on Physiological Characteristics
These
are the genetic and fundamental biochemical and structural components of the
child’s body, brain, and nervous system that are essentially unchangeable.
Note that certain aspects of the biological state may be predictable and/or
preventable at some earlier point in development and as technology improves may
indeed be modifiable. However, at the current state of the art, we must regard
them as unmodifiable. The components of the biological state are DNA (basic
genetic structure), brain and nervous system, sensory and motor organs, the
immune system and all other biological systems.
Genetics:
Advances have been made to find the genes involved communications and learning
disorders (Folstein, Bisson, Santangelo & Piven, 1998). There have been
findings that relatives are affected by difficulties that appear conceptually
related to these disorders (Bailey, Palferman, Heavey & Le Couteur, 1998
& Gilberg, 1998).
Brain
Structure:
Research has demonstrated that the brain of people with communication and
learning disorders is structurally different from the normal brain. They found
abnormalities in the cerebellar vermian lobules, parietal lobe, and the
posterior regions of the corpus callosum (Saitoh & Courchesne, 1998) as well
as intrinsic neocortical dysfunction present in autism (Minshew, Luna &
Sweeney, 1999) and the frontal area of the brain as most involved in ADHD
(Zametkin et al.1990).
Sensory
Motor:
Positron emission tomography (PET) researchers have shown abnormalities in the
language and auditory perception areas of the brain in people with these
disorders (Muller et al. 1999).
Neurotransmitters:
Levels of neurotransmitters such as serotonin and beta-endorphin have been found
to be indicative of the presence of autism and other communication and learning
disorders (Chugani et al. 1999, and Leboyer et al. 1999).
Autoimmune
Disorder:
Research seems to support the hypothesis that a virus-induced autoimmune
response may play a causal role in autism and other communications and learning
disorders (Sing, Lin, & Yang, 1998; Comi et al., 1999; & Connolly et
al., 1999).
All
of the research to date comes to the prevailing view that many of the
communication and learning disorders are caused by a pathophysiologic process
arising from the interaction of an early environmental insult and a genetic
predisposition (Trottier, Srivastava, & Walker, 1999).
Other
factors which impact the physiological state of a child
A
child's physiological state is constantly acted upon by environmental factors. Recently, researchers have investigated how use of
antibiotics (Bolte, 1998), abnormal sleep patterns (Patzold, Richdale &
Tonge, 1998), diet (Carlsson, 1998), medical illness (Volkmar, 1998) and
epilepsy (Kobayashi & Murata) have exacerbated the developmental functioning
of children. These
external factors include:
- The
Womb Environment: the mother's nutrition, stress, antibiotics, drug use-street
or prescribed, alcohol or tobacco abuse, diseases (HIV, CMV, chicken pox etc.),
radiation exposure (pre or post conception)
- The
Birthing Process: use of pitocin, hypoxia
- Food
& Drink: contaminants, food additives, fluoride in water, vitamin
deficiencies
- The
Environment: air, water or noise pollution, vanishing ozone layer, other noxious
stimuli
- Medical
Interventions: vaccinations, inappropriate antibiotics for otitis media (ear
infection) or pharyngitis (sore throat)
- Intentional
modifying factors: brain surgery, medications such as neurotransmitters,
endocrine agents, anti-seizure drugs, steroids
- Plus
other, not yet identified primary therapies that directly manipulate the
biological state and impact on primary traits.
Typically
biochemical interventions are generally targeted at this results of these
impacting factors to
modify an identified or theorized physiological dysfunction.

Step
1: Physiological Assessment Approach
This
assessment should examine: metabolic abnormalities, brain lesions, seizure
activity, and immune disorders. Plus the impact of outside factors such as:
biochemical stressors, contaminants, medications, etc.
Physiological
State Assessment should include:
- Medical
evaluation
- Pediatric
neurological evaluation
- Metabolic/endocrine
screening
- Nutritional
screening
- Genetic
screening

Services
Needed for Physiological State of Child
To
address the physiological factors the follwoing might be needed: Brain
Surgery, Nutrition therapy, Immune Suppression Medications, Anti-seizure
Medications, Stimulant Medication (Ritalin, Cylert, Adderol)

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